Linked Life Data

8592109

Source:http://linkedlifedata.com/resource/pubmed/id/8592109

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1996-4-3
pubmed:abstractText
engrailed (en) is expressed in the posterior region of embryonic segments and appendages of the cockroach, Periplaneta americana. By 23% of embryogenesis En immunoreactivity is apparent in the dorsal half of the cercus, appendages of segment A11. By 40% of development, En staining is present in the dorsomedial half of the cercus. The nucleus of the medial filiform hair sensory neuron (M), born in this region, expresses en strongly. Staining is never seen in the lateral neuron (L). En is expressed in M as the sensory axons enter the terminal ganglion and begin to form their different arborizations and synaptic connections. This pattern of expression persists through development to the second instar. In mutant animals with supernumerary filiform hair sensilla, En immunoreactivity is only seen in the medial neurons. In second-instar and adult cerci en expression is also seen in medially located neurons. We compared the levels of En staining in the array of 25 second instar neurons with their position, axonal arbor type, and synaptic connections. Staining intensity correlates with distance from the cercal midline, suggesting that en is regulated by other circumferential positional determinants. The expression of en does not correlate with the formation of an M-type arbor. Although 10 to 12 sensory neurons that express en form synapses with giant interneuron 5, the correlation is not precise. These results suggest that, if En does form part of a combinatorial system of positional information in the cercus, its actions are modulated by other gene products.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0022-3034
pubmed:author
pubmed:issnType
Print
pubmed:volume
28
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
493-505
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1995
pubmed:articleTitle
Expression of engrailed in an array of identified sensory neurons: comparison with position, axonal arborization, and synaptic connectivity.
pubmed:affiliation
Institute of Neurobiology, University of Puerto Rico Medical Sciences Campus, San Juan 00901.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't