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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
6
|
| pubmed:dateCreated |
1977-6-30
|
| pubmed:abstractText |
Amniotic fluid infections were the most common cause of perinatal death in Addis Ababa, Ethiopia (21.8/1,000 live births). Most such infections appear to originate in the fetal membranes near the cervical os. The high rate of spread of these local infections into the amniotic fluid in Addis Ababa appears related to a lack of antimicrobial activity in amniotic fluids. Factors that adversely affected nutrition in the gravid woman, lack of prenatal medical care, and low water usage were associated with the high rate of fatal infections.
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| pubmed:keyword |
http://linkedlifedata.com/resource/pubmed/keyword/Africa,
http://linkedlifedata.com/resource/pubmed/keyword/Africa South Of The Sahara,
http://linkedlifedata.com/resource/pubmed/keyword/Comparative Studies,
http://linkedlifedata.com/resource/pubmed/keyword/Demographic Factors,
http://linkedlifedata.com/resource/pubmed/keyword/Developing Countries,
http://linkedlifedata.com/resource/pubmed/keyword/Diseases,
http://linkedlifedata.com/resource/pubmed/keyword/Eastern Africa,
http://linkedlifedata.com/resource/pubmed/keyword/Educational Status,
http://linkedlifedata.com/resource/pubmed/keyword/Ethiopia,
http://linkedlifedata.com/resource/pubmed/keyword/Fetal Death,
http://linkedlifedata.com/resource/pubmed/keyword/Incidence,
http://linkedlifedata.com/resource/pubmed/keyword/Infant Mortality,
http://linkedlifedata.com/resource/pubmed/keyword/Infections,
http://linkedlifedata.com/resource/pubmed/keyword/Measurement,
http://linkedlifedata.com/resource/pubmed/keyword/Mortality,
http://linkedlifedata.com/resource/pubmed/keyword/POVERTY,
http://linkedlifedata.com/resource/pubmed/keyword/Population,
http://linkedlifedata.com/resource/pubmed/keyword/Population Characteristics,
http://linkedlifedata.com/resource/pubmed/keyword/Population Dynamics,
http://linkedlifedata.com/resource/pubmed/keyword/Research Methodology,
http://linkedlifedata.com/resource/pubmed/keyword/Retrospective Studies,
http://linkedlifedata.com/resource/pubmed/keyword/Studies,
http://linkedlifedata.com/resource/pubmed/keyword/Urban Population
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
AIM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jun
|
| pubmed:issn |
0022-3476
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
90
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
965-70
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:otherAbstract |
PIP: Congenital pneumonia, originating in an amniotic fluid bacterial infection, is a common cause of perinatal death in industrial societies. A study of perinatal mortality was undertaken in Addis Ababa, Ethiopia, in 1974-1975 in the hospitals and clinics affiliated with the Addis Ababa University Faculty of Medicine. 72% of the perinatal deaths had postmortem examinations and the pregnancies associated with the 1019 autopsied infants were compared with 586 systematically selected successful pregnancies drawn from a cross section of the delivery population by using the 1st deliveries after 7:00 a.m. each day. Hospital and clinic records in conjunction with a detained maternal interview and physical examination on the day following delivery provided 124 separate items of information for analysis. Autopsy prosections and gross placental examinations were performed by 1 Ethiopian and 4 US medical students. Amniotic fluid infection syndrome was identified as the prime diagnosis responsible for deaths in 339 cases for a frequency of 21.8/1000 live births. The fatal disorder had a frequency of 0.10%/week at midgestation with little subsequent change until 39 weeks when it markedly increased. 69% of the deaths were stillborn and the rest neonatal. 76% of lung and 66% of placental cultures were positive for 1 or more organisms in the amniotic fluid infection cases. Only 17% of the placentas from control cases had positive cultures. Fatal amniotic fluid infections had a frequency of 1.75% in single born infants and 12.9% in twins. The fatal infections had a frequency of 1.2% when women made clinic visits for prenatal medical care, and 4.2% when they made no such visits. The disorder was 5 times more frequent in the gravid women who had no education than in those who had 12 or more years of education. The influence of mother's education on the frequency of the fatal infections was largely independent on the influence of poverty. There was an excessive frequency of the fatal infections when women reported prior fetal losses. Acute inflammation of the extraplacental fetal membranes was present in 31% of the control cases, acute funisitis in 11%, and acute inflammation of the chorionic plate of the placenta in 13%. Among the perinatal deaths attributed to amniotic fluid infections, all had congenital pneumonia, 86% acute inflammation of the extraplacental fetal membranes, 61% acute funisitis, and 84% acute inflammation of the chorionic plate of the placenta.
|
| pubmed:meshHeading |
pubmed-meshheading:859070-Amniotic Fluid,
pubmed-meshheading:859070-Diseases in Twins,
pubmed-meshheading:859070-Ethiopia,
pubmed-meshheading:859070-Female,
pubmed-meshheading:859070-Humans,
pubmed-meshheading:859070-Infant, Newborn,
pubmed-meshheading:859070-Pneumonia,
pubmed-meshheading:859070-Poverty,
pubmed-meshheading:859070-Pregnancy,
pubmed-meshheading:859070-Prenatal Care,
pubmed-meshheading:859070-Twins,
pubmed-meshheading:859070-Water Supply
|
| pubmed:year |
1977
|
| pubmed:articleTitle |
Amniotic fluid infections in an African city.
|
| pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
|