Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
16
pubmed:dateCreated
1996-3-25
pubmed:abstractText
In vitro evaluation of antithrombogenicity of materials of artificial vascular vessels was carried out based on an analysis of the coagulation mechanism of blood. Coagulation of blood in tubes coated with endothelial cells (ECs) or segmented polyurethane (SPU) was measured by a rheological technique. Coagulation of blood in hybrid-type vascular vessel model tubes consisting of cultured ECs proliferated on carbon-deposited SPU was also examined. Coagulation of blood in these tubes occurred within 40 min, and appears to be due to the interaction between erythrocytes and a coagulant factor in plasma. From the in vitro evaluation test, when the time of onset of the coagulation of blood in contact with a surface of the artificial materials is longer than 20-39 min, the materials can be considered to provide an inert surface against thrombus formation and blood coagulation.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0142-9612
pubmed:author
pubmed:issnType
Print
pubmed:volume
16
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1229-34
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1995
pubmed:articleTitle
In vitro evaluation of antithrombogenicity of hybrid-type vascular vessel models based on analysis of the mechanism of blood coagulation.
pubmed:affiliation
Institute of Physical and Chemical Research (RIKEN), Saitama, Japan.
pubmed:publicationType
Journal Article, In Vitro