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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
8
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pubmed:dateCreated |
1996-3-27
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pubmed:abstractText |
The development of therapy-related acute myeloid leukemia (t-AML) with balanced translocations to chromosome bands 11q23 and 21q22 has recently been significantly related to previous treatment with several cytostatic drugs poisoning DNA topoisomerase II. A similar association was suspected for other balanced chromosomal aberrations such as the t(15;17) characteristic of acute promyelocytic leukemia (APL).
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0923-7534
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
6
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
781-8
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:8589015-Adult,
pubmed-meshheading:8589015-Antineoplastic Combined Chemotherapy Protocols,
pubmed-meshheading:8589015-Base Sequence,
pubmed-meshheading:8589015-Breast Neoplasms,
pubmed-meshheading:8589015-Female,
pubmed-meshheading:8589015-Humans,
pubmed-meshheading:8589015-Leukemia, Promyelocytic, Acute,
pubmed-meshheading:8589015-Male,
pubmed-meshheading:8589015-Middle Aged,
pubmed-meshheading:8589015-Molecular Sequence Data,
pubmed-meshheading:8589015-Neoplasms, Second Primary,
pubmed-meshheading:8589015-Seminoma,
pubmed-meshheading:8589015-Testicular Neoplasms,
pubmed-meshheading:8589015-Topoisomerase II Inhibitors,
pubmed-meshheading:8589015-Translocation, Genetic
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pubmed:year |
1995
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pubmed:articleTitle |
Therapy-related acute promyelocytic leukemia with t(15;17) (q22;q12) following chemotherapy with drugs targeting DNA topoisomerase II. A report of two cases and a review of the literature.
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pubmed:affiliation |
Laboratory for Cancer Genetics and Cytogenetics, Finsen Center, Rigshospitalet, Copenhagen, Denmark.
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pubmed:publicationType |
Journal Article,
Review,
Case Reports,
Research Support, Non-U.S. Gov't
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