Linked Life Data

8587881

Source:http://linkedlifedata.com/resource/pubmed/id/8587881

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1362
pubmed:dateCreated
1996-3-25
pubmed:abstractText
A recent letter to Nature (Vaadia et al. Nature, Lond. 373, 515-518 (1995)) presented compelling results concerning neuronal interactions in monkey cortex. Vaadia et al. made two fundamental points: (i) it is possible that cortical function is mediated by dynamic modulation of coherent firing among neurons; and (ii) these time-dependent changes in correlations can emerge without modulation of firing rates. These observations have severe implications for models of neural coding and empirical approaches that are based on firing rates (e.g. neuroimaging). This communication presents a simpler explanation for the results presented in Vaadia et al., by noting they are consistent with the correlated expression of stereotyped neuronal transients following (or preceding) a salient event. This re-formulation is important because: (i) correlations measured in terms of transients are not time-dependent, allowing prevailing models of neural coding to be 'reinstated'; and (ii) it suggests a powerful analysis based on singular value decomposition of firing rates.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0962-8452
pubmed:author
pubmed:issnType
Print
pubmed:day
22
pubmed:volume
261
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
401-5
pubmed:dateRevised
2009-9-29
pubmed:meshHeading
pubmed:year
1995
pubmed:articleTitle
Neuronal transients.
pubmed:affiliation
Wellcome Department of Cognitive Neurology, Institute of Neurology, London, U.K.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't