Linked Life Data

8587875

Source:http://linkedlifedata.com/resource/pubmed/id/8587875

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1362
pubmed:dateCreated
1996-3-25
pubmed:abstractText
Strains of Drosophila simulans from Riverside, California (DSR) and Hawaii (DSH) harbour distinct strains of the cytoplasmic incompatibility microorganism Wolbachia, resulting in the expression of bidirectional incompatibility when crossed. D. simulans lines carrying both of these (superinfected) Wolbachia strains were generated by the transfer of infected DSH cytoplasm into DSR embryos by microinjection. The superinfected flies were unidirectionally incompatible with both DSR and DSH individuals. As a result of this pattern, the superinfected state was observed to replace single infections in laboratory populations. The ability of the superinfection to spread was modulated by the production of singly infected offspring from superinfected mothers: strain segregation was observed under crowded larval rearing conditions. An inverse correlation between the penetrance of the cytoplasmic incompatibility phenotype and the degree of larval crowding was also observed. The findings have implications for the evolution of bidirectionally incompatible strains, and lead to the prediction that superinfections should be relatively common in field populations. Evidence for a natural superinfection in the mosquito Aedes albopictus is discussed. The results also have applied significance for the generation of insect lines capable of driving desirable genes into populations already infected with Wolbachia, thus allowing repeated opportunities for population replacement.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0962-8452
pubmed:author
pubmed:issnType
Print
pubmed:day
22
pubmed:volume
261
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
325-30
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1995
pubmed:articleTitle
Wolbachia superinfections and the expression of cytoplasmic incompatibility.
pubmed:affiliation
Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, Connecticut 06520, USA.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't