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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:dateCreated |
1996-3-28
|
| pubmed:abstractText |
Immunoreactive endothelin-1 (ET-1) levels were measured in the pericardial fluid (PF), plasma (PL), and atrial and ventricular tissues of 16 cardiac surgical patients. ET-1 was higher in the PF (73 +/- 11 pg/ml) than in the PL/3.33 +/- 0.51 pg/ml; p < 0.05/. PF/PL ratio ranged from 8 to as high as 200. An inverse relationship was found between the NYHA stage and ET-1 concentrations in PF, whereas ET-1 in PL did not have any relation to the NYHA stage of the disease. In HPLC analysis, the total immunoreactive ET-1 in PF from five different patients co-eluted with the human ET-1 standard. The results indicate that ET-1 concentrations in human PF can be several-fold those in the PL. The source and function of the ET-1 in PF requires further investigation.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0160-2446
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
26 Suppl 3
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
S502-4
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:8587459-Body Fluids,
pubmed-meshheading:8587459-Chromatography, High Pressure Liquid,
pubmed-meshheading:8587459-Endothelins,
pubmed-meshheading:8587459-Female,
pubmed-meshheading:8587459-Humans,
pubmed-meshheading:8587459-Male,
pubmed-meshheading:8587459-Middle Aged,
pubmed-meshheading:8587459-Pericardium
|
| pubmed:year |
1995
|
| pubmed:articleTitle |
Human pericardial fluid contains the highest amount of endothelin-1 of all mammalian biologic fluids thus far tested.
|
| pubmed:affiliation |
Department of Cardiovascular Surgery, Semmelweis Medical University, Budapest, Hungary.
|
| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|