Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1977-6-30
pubmed:abstractText
Chickens were injected posthatching with cyclophosphamide in three different doses (total 8, 10, 11 mg). Histomorphological analysis of bursal tissue was performed up to 11 weeks of age. A probable biphasic recovery was observed in the majority of the chickens. The first phase of recovery is characterized by the appearance of solitary thioninophilic cells in reticuloepithelial follicles, followed in a few follicles by a redevelopment similar to embryonal follicular genesis. The late phase of recovery starts from week 7 on by infiltration of reticuloepithelial follicles with mature plasma cells in the manner of a peripheral lymphoid organ followed by thioninophilic lymphoid cells. The latter cells populate the follicles successively. Different transitions to normal follicles then take place. These investigations confirm observations of a reconstitution of bursal compartments starting some weeks later than the recovery of thymus, which takes place 2 weeks after cyclophosphamide treatment.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0020-5915
pubmed:author
pubmed:issnType
Print
pubmed:volume
53
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
206-13
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1977
pubmed:articleTitle
Recovery of the bursa of Fabricius in chickens after cyclophosphamide treatment: a histological study.
pubmed:publicationType
Journal Article