Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
|
pubmed:dateCreated |
1996-3-25
|
pubmed:databankReference | |
pubmed:abstractText |
A mouse inositol polyphosphate 1-phosphatase (Inpp1) cDNA fragment (348 bp) was amplified by means of the polymerase chain reaction using a mouse cDNA library as template with primers designed from published human and bovine cDNA sequences. We isolated a 1623-bp full-length Inpp1 cDNA from a mouse brain cDNA library using this amplified cDNA fragment as probe. Amino acid sequences of mouse, human, and bovine inositol polyphosphate 1-phosphatase are highly conserved. Northern blot analysis shows a major transcript of 1.65-kb mRNA and several higher molecular weight mRNAs that are expressed in a variety of mouse tissues. Utilizing the Jackson Lab backcross DNA panel map service, we mapped Inpp1 to chromosome 1, 1.06 cM proximal to Ctla4.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Nov
|
pubmed:issn |
0888-7543
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:day |
20
|
pubmed:volume |
30
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
358-60
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:8586440-Amino Acid Sequence,
pubmed-meshheading:8586440-Animals,
pubmed-meshheading:8586440-Base Sequence,
pubmed-meshheading:8586440-Chromosome Mapping,
pubmed-meshheading:8586440-Crosses, Genetic,
pubmed-meshheading:8586440-DNA, Complementary,
pubmed-meshheading:8586440-Humans,
pubmed-meshheading:8586440-Mice,
pubmed-meshheading:8586440-Mice, Inbred C57BL,
pubmed-meshheading:8586440-Molecular Sequence Data,
pubmed-meshheading:8586440-Phosphoric Monoester Hydrolases,
pubmed-meshheading:8586440-Sequence Homology, Amino Acid
|
pubmed:year |
1995
|
pubmed:articleTitle |
Identification and chromosomal mapping of the mouse inositol polyphosphate 1-phosphatase gene.
|
pubmed:affiliation |
Laboratory of Genetic Disease Research, National Institutes of Health, Bethesda, Maryland 20892-4470, USA.
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
|