| pubmed-article:8585749 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:8585749 | lifeskim:mentions | umls-concept:C0042769 | lld:lifeskim |
| pubmed-article:8585749 | lifeskim:mentions | umls-concept:C0029347 | lld:lifeskim |
| pubmed-article:8585749 | lifeskim:mentions | umls-concept:C0521346 | lld:lifeskim |
| pubmed-article:8585749 | lifeskim:mentions | umls-concept:C0026809 | lld:lifeskim |
| pubmed-article:8585749 | lifeskim:mentions | umls-concept:C0027950 | lld:lifeskim |
| pubmed-article:8585749 | lifeskim:mentions | umls-concept:C0677582 | lld:lifeskim |
| pubmed-article:8585749 | lifeskim:mentions | umls-concept:C0445202 | lld:lifeskim |
| pubmed-article:8585749 | lifeskim:mentions | umls-concept:C2348767 | lld:lifeskim |
| pubmed-article:8585749 | lifeskim:mentions | umls-concept:C0355642 | lld:lifeskim |
| pubmed-article:8585749 | pubmed:issue | 11 | lld:pubmed |
| pubmed-article:8585749 | pubmed:dateCreated | 1996-3-20 | lld:pubmed |
| pubmed-article:8585749 | pubmed:abstractText | Polyriboinosinic-polyribocytidylic acid [poly(IC.LC)] was evaluated for its prophylactic and therapeutic efficacies against respiratory influenza A virus infection in mice. Two doses of poly(IC.LC) (1 mg/kg of body weight per dose) administered intranasally within 12 days prior to infection with 10 50% lethal doses of mouse-adapted influenza A/PR/8 virus fully protected the mice against the infection. Determination of virus titers by hemagglutination and plaque assays showed more than a 2-log10 decrease in virus titers in lung homogenates of pretreated mice compared with those in the lungs of the nonpretreated group. Treatment of infected mice with poly(IC.LC) resulted in a modest (40%) survival rate. These results suggest that poly(IC.LC) provides a highly effective prophylaxis against respiratory influenza A virus infection in mice. | lld:pubmed |
| pubmed-article:8585749 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8585749 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8585749 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8585749 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8585749 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8585749 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8585749 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8585749 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8585749 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8585749 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8585749 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8585749 | pubmed:language | eng | lld:pubmed |
| pubmed-article:8585749 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8585749 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:8585749 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8585749 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8585749 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8585749 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8585749 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8585749 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8585749 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8585749 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:8585749 | pubmed:month | Nov | lld:pubmed |
| pubmed-article:8585749 | pubmed:issn | 0066-4804 | lld:pubmed |
| pubmed-article:8585749 | pubmed:author | pubmed-author:KendeMM | lld:pubmed |
| pubmed-article:8585749 | pubmed:author | pubmed-author:LevyH BHB | lld:pubmed |
| pubmed-article:8585749 | pubmed:author | pubmed-author:WongJ PJP | lld:pubmed |
| pubmed-article:8585749 | pubmed:author | pubmed-author:SaravolacE... | lld:pubmed |
| pubmed-article:8585749 | pubmed:author | pubmed-author:SabudaDD | lld:pubmed |
| pubmed-article:8585749 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:8585749 | pubmed:volume | 39 | lld:pubmed |
| pubmed-article:8585749 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:8585749 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:8585749 | pubmed:pagination | 2574-6 | lld:pubmed |
| pubmed-article:8585749 | pubmed:dateRevised | 2011-11-17 | lld:pubmed |
| pubmed-article:8585749 | pubmed:meshHeading | pubmed-meshheading:8585749-... | lld:pubmed |
| pubmed-article:8585749 | pubmed:meshHeading | pubmed-meshheading:8585749-... | lld:pubmed |
| pubmed-article:8585749 | pubmed:meshHeading | pubmed-meshheading:8585749-... | lld:pubmed |
| pubmed-article:8585749 | pubmed:meshHeading | pubmed-meshheading:8585749-... | lld:pubmed |
| pubmed-article:8585749 | pubmed:meshHeading | pubmed-meshheading:8585749-... | lld:pubmed |
| pubmed-article:8585749 | pubmed:meshHeading | pubmed-meshheading:8585749-... | lld:pubmed |
| pubmed-article:8585749 | pubmed:meshHeading | pubmed-meshheading:8585749-... | lld:pubmed |
| pubmed-article:8585749 | pubmed:meshHeading | pubmed-meshheading:8585749-... | lld:pubmed |
| pubmed-article:8585749 | pubmed:meshHeading | pubmed-meshheading:8585749-... | lld:pubmed |
| pubmed-article:8585749 | pubmed:meshHeading | pubmed-meshheading:8585749-... | lld:pubmed |
| pubmed-article:8585749 | pubmed:meshHeading | pubmed-meshheading:8585749-... | lld:pubmed |
| pubmed-article:8585749 | pubmed:meshHeading | pubmed-meshheading:8585749-... | lld:pubmed |
| pubmed-article:8585749 | pubmed:meshHeading | pubmed-meshheading:8585749-... | lld:pubmed |
| pubmed-article:8585749 | pubmed:meshHeading | pubmed-meshheading:8585749-... | lld:pubmed |
| pubmed-article:8585749 | pubmed:year | 1995 | lld:pubmed |
| pubmed-article:8585749 | pubmed:articleTitle | Prophylactic and therapeutic efficacies of poly(IC.LC) against respiratory influenza A virus infection in mice. | lld:pubmed |
| pubmed-article:8585749 | pubmed:affiliation | Medical Countermeasures Section, Defence Research Establishment Suffield, Ralston, Alberta, Canada. | lld:pubmed |
| pubmed-article:8585749 | pubmed:publicationType | Journal Article | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8585749 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8585749 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8585749 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8585749 | lld:pubmed |
