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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1996-3-20
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pubmed:abstractText |
Although Thy-1 is one of the most abundant surface glycoproteins in mammalian central neurons, its functional role is still not clarified. In this study we demonstrate that Thy-1 expression in the rat retina starts only at embryonic day 19 on both the cell somas and processes of retinal ganglion cells. Thy-1 immunoreactivity in the ganglion cell layer increases until postnatal day 14 and is paralleled by an increase in the thickness of the inner plexiform layer. Thus, the beginning of Thy-1 expression is correlated with a developmental stage when axonal elongation and neurite sprouting of ganglion cells has finished and refinement of synaptic structures in the colliculus superior begins. From postnatal day 9 on, Thy-1 immunoreactivity can also be observed on cell somas at the border of the inner plexiform/inner nuclear layer.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0304-3940
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
20
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pubmed:volume |
199
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
91-4
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pubmed:dateRevised |
2003-11-14
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pubmed:meshHeading |
pubmed-meshheading:8584251-Animals,
pubmed-meshheading:8584251-Antigens, Thy-1,
pubmed-meshheading:8584251-Axons,
pubmed-meshheading:8584251-Female,
pubmed-meshheading:8584251-Immunohistochemistry,
pubmed-meshheading:8584251-Pregnancy,
pubmed-meshheading:8584251-Rats,
pubmed-meshheading:8584251-Rats, Inbred BN,
pubmed-meshheading:8584251-Retina,
pubmed-meshheading:8584251-Retinal Ganglion Cells
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pubmed:year |
1995
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pubmed:articleTitle |
Changes in Thy-1 antigen immunoreactivity in the rat retina during pre- and postnatal development.
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pubmed:affiliation |
Abt. II Pathophysiologie des Sehens und Neuro-Opthalmologie, Universitäts-Augenklinik, Tübingen, Germany.
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pubmed:publicationType |
Journal Article
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