| pubmed-article:8582664 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:8582664 | lifeskim:mentions | umls-concept:C0026030 | lld:lifeskim |
| pubmed-article:8582664 | lifeskim:mentions | umls-concept:C1882726 | lld:lifeskim |
| pubmed-article:8582664 | lifeskim:mentions | umls-concept:C0030054 | lld:lifeskim |
| pubmed-article:8582664 | lifeskim:mentions | umls-concept:C0053396 | lld:lifeskim |
| pubmed-article:8582664 | lifeskim:mentions | umls-concept:C0033095 | lld:lifeskim |
| pubmed-article:8582664 | lifeskim:mentions | umls-concept:C0441655 | lld:lifeskim |
| pubmed-article:8582664 | pubmed:issue | 6 | lld:pubmed |
| pubmed-article:8582664 | pubmed:dateCreated | 1996-3-21 | lld:pubmed |
| pubmed-article:8582664 | pubmed:abstractText | The effects of the partial pressure of oxygen (pO2) on antioxidant efficiency of beta-carotene in inhibiting 2,2'-azobis(2-amindinopropane) (AAPH)-induced lipid peroxidation are investigated in rat liver microsomal membranes. The rate of peroxyl radicals generated by thermolysis of AAPH at 37 degrees C is markedly higher at 150 than 760 mm Hg pO2. At 150 mm Hg Po2 beta-carotene acts as an antioxidant, inhibiting 2,2'-azobis(2-amidinopropane) 9AAPH0-induced Malonidaldehyde (MDA) formation. At 760 mm Hg Po2, it loses its antioxidant activity and shows a prooxidant effect, increasing lipid peroxidation products. alpha-Tocopherol prevents the prooxidant effect of beta-carotene in a dose-dependent manner. Our data provide the first evidence of a prooxidant effect of beta-carotene under 100% oxygen pressure in a biological membrane model and point out the existence of cooperative interactions between beta-carotene and alpha-tocopherol. | lld:pubmed |
| pubmed-article:8582664 | pubmed:language | eng | lld:pubmed |
| pubmed-article:8582664 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8582664 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:8582664 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8582664 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8582664 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8582664 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8582664 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8582664 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8582664 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8582664 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8582664 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8582664 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:8582664 | pubmed:month | Dec | lld:pubmed |
| pubmed-article:8582664 | pubmed:issn | 0891-5849 | lld:pubmed |
| pubmed-article:8582664 | pubmed:author | pubmed-author:BartoliG MGM | lld:pubmed |
| pubmed-article:8582664 | pubmed:author | pubmed-author:CalvielloGG | lld:pubmed |
| pubmed-article:8582664 | pubmed:author | pubmed-author:PalozzaPP | lld:pubmed |
| pubmed-article:8582664 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:8582664 | pubmed:volume | 19 | lld:pubmed |
| pubmed-article:8582664 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:8582664 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:8582664 | pubmed:pagination | 887-92 | lld:pubmed |
| pubmed-article:8582664 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:8582664 | pubmed:meshHeading | pubmed-meshheading:8582664-... | lld:pubmed |
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| pubmed-article:8582664 | pubmed:meshHeading | pubmed-meshheading:8582664-... | lld:pubmed |
| pubmed-article:8582664 | pubmed:year | 1995 | lld:pubmed |
| pubmed-article:8582664 | pubmed:articleTitle | Prooxidant activity of beta-carotene under 100% oxygen pressure in rat liver microsomes. | lld:pubmed |
| pubmed-article:8582664 | pubmed:affiliation | Institute of General Pathology, Catholic University, Rome, Italy. | lld:pubmed |
| pubmed-article:8582664 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:8582664 | pubmed:publicationType | Comparative Study | lld:pubmed |
| pubmed-article:8582664 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8582664 | lld:pubmed |
