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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1-2
|
pubmed:dateCreated |
1996-3-20
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pubmed:abstractText |
We previously demonstrated that adult rats prenatally exposed to ethanol display permanent damages of thalamo-cortical connections [18,19,33]. Here the effect of simultaneous administration of ethanol and acetyl-L-carnitine has been investigated. Adult animals underwent cortical or thalamic injections of horseradish peroxidase and both anterograde and retrograde thalamic and cortical labeling have been analyzed. Ethanol-induced changes of thalamo-cortical circuits are prevented by concurrent administration of acetyl-L-carnitine. Possible mechanisms underlying this effect are discussed.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0006-8993
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
6
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pubmed:volume |
698
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
241-7
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:8581491-Acetylcarnitine,
pubmed-meshheading:8581491-Animals,
pubmed-meshheading:8581491-Ethanol,
pubmed-meshheading:8581491-Female,
pubmed-meshheading:8581491-Horseradish Peroxidase,
pubmed-meshheading:8581491-Microinjections,
pubmed-meshheading:8581491-Nootropic Agents,
pubmed-meshheading:8581491-Pregnancy,
pubmed-meshheading:8581491-Prenatal Exposure Delayed Effects,
pubmed-meshheading:8581491-Rats,
pubmed-meshheading:8581491-Somatosensory Cortex,
pubmed-meshheading:8581491-Thalamus
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pubmed:year |
1995
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pubmed:articleTitle |
Alterations of the thalamo-cortical system in rats prenatally exposed to ethanol are prevented by concurrent administration of acetyl-L-carnitine.
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pubmed:affiliation |
Department of Neurological and Psychiatric Sciences, University of Florence, Italy.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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