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rdf:type |
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lifeskim:mentions |
|
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pubmed:issue |
8
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|
pubmed:dateCreated |
1996-3-15
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pubmed:abstractText |
A capillary electrophoresis method has been developed and validated for the analysis of a wide range of basic drugs. Acceptable precision was obtained by employing an internal standard. Optimal sensitivity was obtained using low UV wavelengths. An experimentally designed study showed the method to be robust. The method has advantages over HPLC in terms of simplicity, speed and cost. The method is now in routine use for identity confirmation and assay of both drug substance and formulations.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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pubmed:month |
Jul
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|
pubmed:issn |
0731-7085
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pubmed:author |
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|
pubmed:issnType |
Print
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pubmed:volume |
13
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
951-7
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pubmed:dateRevised |
2000-12-18
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pubmed:meshHeading |
pubmed-meshheading:8580154-Buffers,
pubmed-meshheading:8580154-Drug Stability,
pubmed-meshheading:8580154-Electrophoresis, Capillary,
pubmed-meshheading:8580154-Histamine,
pubmed-meshheading:8580154-Hydrogen-Ion Concentration,
pubmed-meshheading:8580154-Pharmaceutical Preparations,
pubmed-meshheading:8580154-Reference Standards,
pubmed-meshheading:8580154-Reproducibility of Results,
pubmed-meshheading:8580154-Solutions,
pubmed-meshheading:8580154-Spectrophotometry, Ultraviolet
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|
pubmed:year |
1995
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pubmed:articleTitle |
Validated capillary electrophoresis method for the assay of a range of basic drugs.
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|
pubmed:affiliation |
Analytical Evaluation Group, Glaxo Research and Development, Ware, Herts, UK.
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pubmed:publicationType |
Journal Article
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