Linked Life Data

8578998

Source:http://linkedlifedata.com/resource/pubmed/id/8578998

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1996-3-12
pubmed:abstractText
We characterized protective immune response in mice infected with the attenuated Japanese encephalitis virus (JEV) strain SA(A) derived from the live JE vaccine strain SA14-14-2. In the sera of mice infected with SA(A), antibodies to JEV envelope (E) and non-structural NS1 proteins were detected by Western blot analysis and neutralization, haemagglutination-inhibition (HAI), and complement fixation (CF) antibodies were detected by serological tests. Production of antibody to NS1 protein strongly indicated peripheral growth of SA(A) in mice and its growth induced the immune response. A single immunization with SA(A) significantly protected mice against lethal intracerebral (ic) challenge with the virulent SA(V) strain.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0001-723X
pubmed:author
pubmed:issnType
Print
pubmed:volume
39
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
161-4
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1995
pubmed:articleTitle
Immune response in mice infected with the attenuated Japanese encephalitis vaccine strain SA14-14-2.
pubmed:affiliation
Research Center for Biologicals, Kitasato Institute, Saitama, Japan.
pubmed:publicationType
Journal Article