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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1996-3-13
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pubmed:abstractText |
The sensitivity of the most recent generation of anti-hepatitis C virus (anti-HCV) screening tests from seven manufacturers was evaluated with a common panel of 530 specimens from 320 HCV-infected subjects. This panel included 221 samples from 57 seroconverters (53 pre-sero conversion negative specimens and 168 positive samples) and 309 selected specimens from 263 other HCV-infected patients of which 19% exhibited NS3 or core reactivity alone with the presence of HCV-RNA assessed by PCR. None of the seven screening tests detected all infectious and antibody-positive specimens. However, important differences were observed between these assays in the number of false-negative results, which seemed mainly due to nonreactivity of antibody to the NS3 antigen.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0042-9007
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
69
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
213-6
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:8578733-Antigen-Antibody Reactions,
pubmed-meshheading:8578733-Evaluation Studies as Topic,
pubmed-meshheading:8578733-France,
pubmed-meshheading:8578733-Hepacivirus,
pubmed-meshheading:8578733-Hepatitis C,
pubmed-meshheading:8578733-Hepatitis C Antibodies,
pubmed-meshheading:8578733-Humans,
pubmed-meshheading:8578733-Laboratories,
pubmed-meshheading:8578733-Mass Screening,
pubmed-meshheading:8578733-Predictive Value of Tests,
pubmed-meshheading:8578733-Sensitivity and Specificity
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pubmed:year |
1995
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pubmed:articleTitle |
A comparative evaluation of the sensitivity of seven anti-hepatitis C virus screening tests.
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pubmed:affiliation |
Institut National de Transfusion Sanguine, Paris, France.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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