| pubmed-article:8577403 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:8577403 | lifeskim:mentions | umls-concept:C0034721 | lld:lifeskim |
| pubmed-article:8577403 | lifeskim:mentions | umls-concept:C0034693 | lld:lifeskim |
| pubmed-article:8577403 | lifeskim:mentions | umls-concept:C0019564 | lld:lifeskim |
| pubmed-article:8577403 | lifeskim:mentions | umls-concept:C0019588 | lld:lifeskim |
| pubmed-article:8577403 | lifeskim:mentions | umls-concept:C0079883 | lld:lifeskim |
| pubmed-article:8577403 | lifeskim:mentions | umls-concept:C1709059 | lld:lifeskim |
| pubmed-article:8577403 | lifeskim:mentions | umls-concept:C1533691 | lld:lifeskim |
| pubmed-article:8577403 | lifeskim:mentions | umls-concept:C0521116 | lld:lifeskim |
| pubmed-article:8577403 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:8577403 | pubmed:dateCreated | 1996-3-13 | lld:pubmed |
| pubmed-article:8577403 | pubmed:abstractText | Modulation of excitatory postsynaptic currents by histamine was examined using whole cell recording methods in the CA1 region of slices of rat hippocampus. Histamine affected the N-methyl-D-aspartate (NMDA) component of the synaptic current in a pH-dependent manner: at lowered pH (7.2) it enhanced the NMDA-mediated synaptic currents while at raised pH (7.6) it reduced them. At a pH of 7.4 there was no significant action of histamine. Histamine failed to alter the non-NMDA component of the synaptic current. These results indicate that histamine acts at a postsynaptic site to modulate NMDA mediated synaptic currents in a pH dependent manner. This mechanism may have important implications for the pathophysiology of shifts in extracellular pH. | lld:pubmed |
| pubmed-article:8577403 | pubmed:language | eng | lld:pubmed |
| pubmed-article:8577403 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8577403 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:8577403 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8577403 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8577403 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:8577403 | pubmed:month | Oct | lld:pubmed |
| pubmed-article:8577403 | pubmed:issn | 0304-3940 | lld:pubmed |
| pubmed-article:8577403 | pubmed:author | pubmed-author:HaasH LHL | lld:pubmed |
| pubmed-article:8577403 | pubmed:author | pubmed-author:StevensD RDR | lld:pubmed |
| pubmed-article:8577403 | pubmed:author | pubmed-author:SaybasiliHH | lld:pubmed |
| pubmed-article:8577403 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:8577403 | pubmed:day | 27 | lld:pubmed |
| pubmed-article:8577403 | pubmed:volume | 199 | lld:pubmed |
| pubmed-article:8577403 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:8577403 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:8577403 | pubmed:pagination | 225-7 | lld:pubmed |
| pubmed-article:8577403 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:8577403 | pubmed:meshHeading | pubmed-meshheading:8577403-... | lld:pubmed |
| pubmed-article:8577403 | pubmed:meshHeading | pubmed-meshheading:8577403-... | lld:pubmed |
| pubmed-article:8577403 | pubmed:meshHeading | pubmed-meshheading:8577403-... | lld:pubmed |
| pubmed-article:8577403 | pubmed:meshHeading | pubmed-meshheading:8577403-... | lld:pubmed |
| pubmed-article:8577403 | pubmed:meshHeading | pubmed-meshheading:8577403-... | lld:pubmed |
| pubmed-article:8577403 | pubmed:meshHeading | pubmed-meshheading:8577403-... | lld:pubmed |
| pubmed-article:8577403 | pubmed:meshHeading | pubmed-meshheading:8577403-... | lld:pubmed |
| pubmed-article:8577403 | pubmed:meshHeading | pubmed-meshheading:8577403-... | lld:pubmed |
| pubmed-article:8577403 | pubmed:meshHeading | pubmed-meshheading:8577403-... | lld:pubmed |
| pubmed-article:8577403 | pubmed:year | 1995 | lld:pubmed |
| pubmed-article:8577403 | pubmed:articleTitle | pH-dependent modulation of N-methyl-D-aspartate receptor-mediated synaptic currents by histamine in rat hippocampus in vitro. | lld:pubmed |
| pubmed-article:8577403 | pubmed:affiliation | Physiologisches Institut II, Heinrich-Heine-Universität, Düsseldorf, Germany. | lld:pubmed |
| pubmed-article:8577403 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:8577403 | pubmed:publicationType | In Vitro | lld:pubmed |
| pubmed-article:8577403 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
