Linked Life Data

8577146

Source:http://linkedlifedata.com/resource/pubmed/id/8577146

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1996-3-8
pubmed:abstractText
The mathematical model of the dynamics of humoral immune responses to soluble antigens has been developed. This is a system of nonlinear differential equations describing concentrations of immunocompetent B-lymphocytes, plasma cells, antibodies and antigen. The model reproduces cyclic kinetics of the immune reaction to slowly catabolizing antigens which is observed experimentally. Within the framework of the model a description of the mechanism of origin of oscillatory modes of the dynamics of the immune response is presented. It has been shown that the feedback in the control of the antibody synthesis by antibodies is due to neutralization of the main stimulus of the immune system, i.e., free molecules of the antigen--by circulating antibodies.
pubmed:language
rus
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0321-5040
pubmed:author
pubmed:issnType
Print
pubmed:volume
25
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
53-6
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:articleTitle
[Study of cyclic kinetics of immunity by mathematical modeling methods].
pubmed:publicationType
Journal Article, Comparative Study, English Abstract