Linked Life Data

8576423

Source:http://linkedlifedata.com/resource/pubmed/id/8576423

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1996-3-13
pubmed:abstractText
Most sympathetic postganglionic noradrenergic varicosities of the perivascular plexus of small muscular arteries in laboratory mammals make contact with the outer smooth muscle cells of the media at neuromuscular junctions. These neurovascular junctions have most of the characteristics of those in skeletal muscle. In the rat tail artery, which bears a particularly dense perivascular plexus, many studies indicate that both purinergic and noradrenergic mechanisms underlie neurally mediated vasoconstriction. We have examined the relationship of large axonal varicosities to the smooth muscle surface of proximal parts of this vessel using three-dimensional reconstructions from serial thin sections photographed in the electron microscope. Unlike in small arterioles, less than 50% of the large photographed in the electron microscope. Unlike in small arterioles, less than 50% of the large varicosities lying within 1 micron of the outer surface of this artery were found to make neuromuscular junctions. In some non-contacting varicosities, accumulations of synaptic vesicles were aggregated toward axonal membrane which was bare of Schwann cell toward the vessel surface. Prejunctional membrane specializations were detected at 20% of contacting and 12% of non-contacting varicosities. All of the latter lay close (< 350nm) to the smooth muscle. These anatomical data suggest that, in the rat tail artery, transmitter release by exocytosis may occur from both types of varicosity.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0021-9967
pubmed:author
pubmed:issnType
Print
pubmed:day
30
pubmed:volume
361
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
699-709
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1995
pubmed:articleTitle
Proportions and structure of contacting and non-contacting varicosities in the perivascular plexus of the rat tail artery.
pubmed:affiliation
Baker Medical Research Institute, Prahran, Victoria, Australia.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't