pubmed-article:8574897 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:8574897 | lifeskim:mentions | umls-concept:C0008643 | lld:lifeskim |
pubmed-article:8574897 | lifeskim:mentions | umls-concept:C0887889 | lld:lifeskim |
pubmed-article:8574897 | lifeskim:mentions | umls-concept:C0008665 | lld:lifeskim |
pubmed-article:8574897 | lifeskim:mentions | umls-concept:C1880022 | lld:lifeskim |
pubmed-article:8574897 | pubmed:issue | 2 | lld:pubmed |
pubmed-article:8574897 | pubmed:dateCreated | 1996-3-12 | lld:pubmed |
pubmed-article:8574897 | pubmed:abstractText | Selection of chromosomal sublibraries from total human genomic libraries is critical for chromosome-based physical mapping approaches. We have previously reported a method of screening total human genomic library using flow sorted chromosomal DNA as a hybridization probe and selection of a human chromosome 22-enriched sublibrary from a total human bacterial artificial chromosome (BAC) library (Nucleic Acids Res 1995; 23: 1838-39). We describe here further details of the method of construction as well as characterization of the chromosome 22-enriched sublibrary thus constructed. Nearly 40% of the BAC clones that have been mapped by fluorescence in situ hybridization (FISH) analysis were localized to chromosome 22. By screening the sublibrary using chromosome 22-specific hybridization probes, we estimated that the sublibrary represents at least 2.5 x coverage of chromosome 22. This is in good agreement with the results from FISH mapping experiments. FISH map data also indicate that chromosome 22-specific BACs in the sublibrary represent all the subregions of chromosome 22. | lld:pubmed |
pubmed-article:8574897 | pubmed:language | eng | lld:pubmed |
pubmed-article:8574897 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:8574897 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:8574897 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:8574897 | pubmed:month | Oct | lld:pubmed |
pubmed-article:8574897 | pubmed:author | pubmed-author:SolomonJJ | lld:pubmed |
pubmed-article:8574897 | pubmed:author | pubmed-author:SimonM IMI | lld:pubmed |
pubmed-article:8574897 | pubmed:author | pubmed-author:DeavenLL | lld:pubmed |
pubmed-article:8574897 | pubmed:author | pubmed-author:ShizuyaHH | lld:pubmed |
pubmed-article:8574897 | pubmed:author | pubmed-author:ChenX NXN | lld:pubmed |
pubmed-article:8574897 | pubmed:author | pubmed-author:KimU JUJ | lld:pubmed |
pubmed-article:8574897 | pubmed:author | pubmed-author:KorenbergJJ | lld:pubmed |
pubmed-article:8574897 | pubmed:author | pubmed-author:SpeicherSS | lld:pubmed |
pubmed-article:8574897 | pubmed:volume | 12 | lld:pubmed |
pubmed-article:8574897 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:8574897 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:8574897 | pubmed:pagination | 73-9 | lld:pubmed |
pubmed-article:8574897 | pubmed:dateRevised | 2004-11-17 | lld:pubmed |
pubmed-article:8574897 | pubmed:meshHeading | pubmed-meshheading:8574897-... | lld:pubmed |
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pubmed-article:8574897 | pubmed:meshHeading | pubmed-meshheading:8574897-... | lld:pubmed |
pubmed-article:8574897 | pubmed:meshHeading | pubmed-meshheading:8574897-... | lld:pubmed |
pubmed-article:8574897 | pubmed:meshHeading | pubmed-meshheading:8574897-... | lld:pubmed |
pubmed-article:8574897 | pubmed:meshHeading | pubmed-meshheading:8574897-... | lld:pubmed |
pubmed-article:8574897 | pubmed:meshHeading | pubmed-meshheading:8574897-... | lld:pubmed |
pubmed-article:8574897 | pubmed:year | 1995 | lld:pubmed |
pubmed-article:8574897 | pubmed:articleTitle | Characterization of a human chromosome 22 enriched bacterial artificial chromosome sublibrary. | lld:pubmed |
pubmed-article:8574897 | pubmed:affiliation | Division of Biology and Beckmann Institute, California Institute of Technology, Pasadena 91125, USA. | lld:pubmed |
pubmed-article:8574897 | pubmed:publicationType | Journal Article | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:8574897 | lld:pubmed |