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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
1979-6-29
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pubmed:abstractText |
A polypeptide (p40) of approximately 40,000 molecular weight was isolated from herpes simplex virus type 1 and 2 nucleocapsids by gel filtration and ion exchange chromatography. This protein appears to be the same as protein 22a described previously (Gibson and Roizman, J. Virol. 10:1044--1052, 1972). Competition immunoassays were developed by using purified p40 and antisera prepared in guinea pigs. The assays indicated that the p40's from herpes simplex virus types 1 and 2 possess both type-specific and cross-reactive antigenic determinants. Antibodies to the p40 cross-reactive determinant reacted with antigens in simian herpes virus SA8-infected cells, but not with antigens induced by pseudorabies virus. Preliminary results indicated that a radioimmunoprecipitation test can be used to detect type-specific herpes simplex virus p40 antibodies in human sera.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/85720-1167720,
http://linkedlifedata.com/resource/pubmed/commentcorrection/85720-14097352,
http://linkedlifedata.com/resource/pubmed/commentcorrection/85720-166500,
http://linkedlifedata.com/resource/pubmed/commentcorrection/85720-175946,
http://linkedlifedata.com/resource/pubmed/commentcorrection/85720-213527,
http://linkedlifedata.com/resource/pubmed/commentcorrection/85720-4102562,
http://linkedlifedata.com/resource/pubmed/commentcorrection/85720-4132223,
http://linkedlifedata.com/resource/pubmed/commentcorrection/85720-4301411,
http://linkedlifedata.com/resource/pubmed/commentcorrection/85720-4326538,
http://linkedlifedata.com/resource/pubmed/commentcorrection/85720-4344252,
http://linkedlifedata.com/resource/pubmed/commentcorrection/85720-4357511,
http://linkedlifedata.com/resource/pubmed/commentcorrection/85720-4826204,
http://linkedlifedata.com/resource/pubmed/commentcorrection/85720-5432063,
http://linkedlifedata.com/resource/pubmed/commentcorrection/85720-5824574
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0022-538X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
29
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
34-42
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:85720-Antibodies, Viral,
pubmed-meshheading:85720-Antigens, Viral,
pubmed-meshheading:85720-Capsid,
pubmed-meshheading:85720-Cross Reactions,
pubmed-meshheading:85720-Epitopes,
pubmed-meshheading:85720-Herpesviridae,
pubmed-meshheading:85720-Herpesvirus 1, Suid,
pubmed-meshheading:85720-Immunoassay,
pubmed-meshheading:85720-Peptides,
pubmed-meshheading:85720-Simplexvirus,
pubmed-meshheading:85720-Viral Proteins
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pubmed:year |
1979
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pubmed:articleTitle |
Isolation of a nucleocapsid polypeptide of herpes simplex virus types 1 and 2 possessing immunologically type-specific and cross-reactive determinants.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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