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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1996-3-7
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pubmed:abstractText |
Seven untrained male subjects [age 25.6 +/- 1.5 (SE) yr, peak O2 uptake (VO2) 3.20 +/- 0.19 l/min] trained on a cycle ergometer 4 days/wk for 6 wk, with the absolute training workload held constant for the duration of training. Before and at the end of each week of training, the subjects performed 20 min of constant-power exercise at a power designed to elicit a pronounced slow component of VO2 (end-exercise VO2-VO2 at minute 3 of exercise) in the pretraining session. An additional 20-min exercise bout was performed after training at this same absolute power output during which epinephrine (Epi) was infused at a rate of 100 ng.kg-1.min-1 between minutes 10 and 20. After 2 wk of training, significant decreases in VO2 slow component, end-exercise VO2, blood lactate ([La-] and glucose concentrations, plasma Epi ([Epi]) and norepinephrine concentrations, ventilation (VE), and heart rate (HR) were observed (P < 0.05). Although the rapid attenuation of the VO2 slow component coincided temporally with reductions in plasma [Epi], blood [La-], and VE, the infusion of Epi after training significantly increased plasma [Epi] (delta 2.22 ng/ml), blood [La-] (delta 2.4 mmol/l) and VE (delta 10.0 l/min) without any change in exercise VO2. We therefore conclude that diminution of the VO2 slow component with training is attributable to factors other than the reduction in plasma [Epi], blood [La-] and VE.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Epinephrine,
http://linkedlifedata.com/resource/pubmed/chemical/Lactates,
http://linkedlifedata.com/resource/pubmed/chemical/Lactic Acid,
http://linkedlifedata.com/resource/pubmed/chemical/Norepinephrine,
http://linkedlifedata.com/resource/pubmed/chemical/Sympathomimetics
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
8750-7587
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
79
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
838-45
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:8567526-Adaptation, Physiological,
pubmed-meshheading:8567526-Adult,
pubmed-meshheading:8567526-Epinephrine,
pubmed-meshheading:8567526-Exercise,
pubmed-meshheading:8567526-Heart Rate,
pubmed-meshheading:8567526-Humans,
pubmed-meshheading:8567526-Infusions, Intravenous,
pubmed-meshheading:8567526-Lactates,
pubmed-meshheading:8567526-Lactic Acid,
pubmed-meshheading:8567526-Male,
pubmed-meshheading:8567526-Norepinephrine,
pubmed-meshheading:8567526-Oxygen Consumption,
pubmed-meshheading:8567526-Pulmonary Gas Exchange,
pubmed-meshheading:8567526-Respiratory Function Tests,
pubmed-meshheading:8567526-Sympathomimetics
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pubmed:year |
1995
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pubmed:articleTitle |
Slow component of O2 uptake during heavy exercise: adaptation to endurance training.
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pubmed:affiliation |
Exercise Physiology Laboratory, University of Virginia, Charlottesville 22903, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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