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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1-2
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pubmed:dateCreated |
1996-3-5
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pubmed:abstractText |
In the unanesthetized mustached bat, stimulation of the ear with an acoustic transient produces damped oscillations which are evident in the cochlear microphonic potential. In this report we demonstrate how the decay time of these oscillations is affected by broadband noise presented to the contralateral ear (CLN). In the absence of CLN, the mean decay time was 1.94 +/- 0.23 ms, but during the presentation of CLN the decay time consistently decreased. The changes were finely graded, the higher the CLN, the greater the change. The effect could be maintained at a constant level for extended periods of time and this was evident when the CLN exceeded 40 dB SPL. The latency of the reflex for 64 dB noise was about 11 ms and near maximum changes occurred within 15 ms of CLN onset. Sectioning medial efferent nerve fibers in the floor of the fourth ventricle or the administration of a single dose of gentamicin eliminated changes produced by CLN. The prominence of CM responses to damped oscillations and the robust changes in response to CLN make the mustached bat an excellent model for studying the influence of the medial efferent system on cochlear mechanics.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0378-5955
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
86
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
111-24
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:8567408-Acoustic Stimulation,
pubmed-meshheading:8567408-Animals,
pubmed-meshheading:8567408-Anti-Bacterial Agents,
pubmed-meshheading:8567408-Chiroptera,
pubmed-meshheading:8567408-Cochlea,
pubmed-meshheading:8567408-Cochlear Microphonic Potentials,
pubmed-meshheading:8567408-Electrodes, Implanted,
pubmed-meshheading:8567408-Gentamicins,
pubmed-meshheading:8567408-Muscle Contraction,
pubmed-meshheading:8567408-Muscles,
pubmed-meshheading:8567408-Nerve Fibers,
pubmed-meshheading:8567408-Neurons, Efferent,
pubmed-meshheading:8567408-Patch-Clamp Techniques,
pubmed-meshheading:8567408-Sound Localization
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pubmed:year |
1995
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pubmed:articleTitle |
The effect of contralateral stimulation on cochlear resonance and damping in the mustached bat: the role of the medial efferent system.
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pubmed:affiliation |
Department of Cell Biology and Anatomy, University of North Carolina at Chapel Hill 27599, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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