Linked Life Data

8566883

Source:http://linkedlifedata.com/resource/pubmed/id/8566883

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1996-3-7
pubmed:abstractText
The Hemox-Analyzer (TCS, Medical Products Division, Southampton, PA) is an automatic system for determining the oxyhemoglobin dissociation curve (ODC) and P50 values. The ODC is recorded during deoxygenation with nitrogen gas and plotted on graph paper; the oxygen tension is detected by a Clark electrode, while the oxyhemoglobin fraction (%HbO2) is evaluated by a dual-wavelength spectrophotometer. Even though this instrument has been commercially available for more than 20 years, its performance characteristics have been assessed. We evaluated the performance characteristics of the Hemox-Analyzer. P50 was tested in 28 healthy volunteers, in 16 anemic and in 9 polycythemic patients. To test its precision we evaluated both inter- and intra-assay variability. The system shows good precision: standard deviation was 0.39 for assays in duplicate, CV = 1.9% for intra-assay and CV = 3.0% for inter-assay measurements. The mean P50 values were 25.2 +/- 1.5 mmHg in normal volunteers and 27.3 +/- 1.4 mmHg in anemic patients. The Hemox-Analyzer is a simple, quick and reliable instrument for recording the oxyhemoglobin dissociation curve. Both the P50 value and observation of the fine structure of the curve can furnish information about the delivery of oxygen to tissues.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0390-6078
pubmed:author
pubmed:issnType
Print
pubmed:volume
80
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
426-30
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:articleTitle
Performance characteristics of Hemox-Analyzer for assessment of the hemoglobin dissociation curve.
pubmed:affiliation
Istituto di Medicina Interna e Oncologia Medica, IRCCS Policlinico S. Matteo, Pavia, Italy.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't