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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
1996-3-4
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pubmed:abstractText |
Smooth muscle cells resident in the intestinal wall play a significant role in the healing of the injured intestine and in the fibrosis that complicates Crohn's disease. The cytokine interleukin 1 beta (IL-1 beta) is involved in inflammatory bowel disease. The aim of this study was to determine the action of IL-1 beta on proliferation and collagen metabolism in human intestinal smooth muscle cells.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0016-5085
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
110
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
344-50
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:8566579-Blotting, Northern,
pubmed-meshheading:8566579-Cell Division,
pubmed-meshheading:8566579-Collagen,
pubmed-meshheading:8566579-Collagenases,
pubmed-meshheading:8566579-Down-Regulation,
pubmed-meshheading:8566579-Humans,
pubmed-meshheading:8566579-Interleukin-1,
pubmed-meshheading:8566579-Intestines,
pubmed-meshheading:8566579-Muscle, Smooth,
pubmed-meshheading:8566579-Platelet-Derived Growth Factor,
pubmed-meshheading:8566579-Procollagen,
pubmed-meshheading:8566579-RNA, Messenger
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pubmed:year |
1996
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pubmed:articleTitle |
Interleukin 1 beta down-regulates collagen and augments collagenase expression in human intestinal smooth muscle cells.
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pubmed:affiliation |
Department of Pediatrics and Surgery, Medical College of Virginia, Virginia Commonwealth University, Richmond, USA. MGRAHAM@gems.vcu.edu.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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