Linked Life Data

856589

Source:http://linkedlifedata.com/resource/pubmed/id/856589

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1977-6-11
pubmed:abstractText
18 newborn rats received two electroshock seizures daily for 10 days. Their neurochemical and behavioral development was compared to that of littermates fo the same sex and similar weight, which were either untreated or treated with the same total amount of electrical current at subconvulsive intensities. While the two control groups were behaviorially or neurochemically indistinguishable, experimental rats reached several behavioral milestones (swimming, free-fall righting, auditory startle, visual placing) significantly later than controls and had smaller brains, containing significantly less DNA, protein or cholesterol than either control group. This study demonstrates that in the rat neonatal seizures are followed not only by impaired neurochemical development of the brain but also by delays in the animal's behavioral development.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0014-3022
pubmed:author
pubmed:issnType
Print
pubmed:volume
15
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
9-19
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1977
pubmed:articleTitle
Effects of neonatal seizures on ontogeny of reflexes and behavior. An experimental study in the rat.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.