Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
10
pubmed:dateCreated
1996-3-5
pubmed:abstractText
Vascular endothelial cells play an important role in modulating cardiovascular function, by liberating several vasoactive substances, such as prostacyclin, endothelium-derived relaxing factor/nitric oxide, a hyperpolarizing substance, and vasoconstrictor substances. Their roles in the cardiovascular system include modulation of the contraction of the underlying vascular smooth muscle, interaction between blood components and blood vessel wall, vascular growth, as well as regulation of the cardiovascular system at several levels beyond the vascular wall. Alterations in the endothelial functions and the related processes are now known to be involved in the pathogenesis of many cardiovascular diseases, including hypertension and atherosclerosis. Thus, the impaired endothelial regulation of the cardiovascular system may have an important implication for the development and progression of many cardiovascular diseases.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0918-2918
pubmed:author
pubmed:issnType
Print
pubmed:volume
34
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
939-46
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
1995
pubmed:articleTitle
Endothelium-dependent regulation of the cardiovascular system.
pubmed:affiliation
Research Institute of Angiocardiology, Kyushu University School of Medicine, Fukuoka.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Review, Research Support, Non-U.S. Gov't