Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1996-2-21
pubmed:abstractText
In order to determine whether apoptosis contributes to the neuronal loss in scrapie, in situ end labeling was applied on brains of mice showing clinical signs of the disease. Positively labeled, apoptotic neurons were observed in the cerebellum, cerebral cortex and hippocampus, areas known to show characteristic scrapie-related vacuolation, and were absent in the brains of control mice. We conclude that apoptosis plays a role in the neuronal loss that occurs in scrapie. The importance of apoptosis as a predominant cell death mechanism in scrapie, however, remains to be determined.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0304-3940
pubmed:author
pubmed:issnType
Print
pubmed:day
6
pubmed:volume
198
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
185-8
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1995
pubmed:articleTitle
Detection of apoptosis in murine scrapie.
pubmed:affiliation
Graduate School of Neurosciences Amsterdam, Netherlands Institute for Brain Research, The Netherlands.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't