Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1996-2-22
pubmed:abstractText
Nitric oxide (NO) dependent regulation of blood flow has hitherto not been demonstrated in rainbow trout or other salmonid fish. Through in vivo observations of the brain surface (optic lobes) of rainbow trout (Oncorhynchus mykiss) with epi-illumination microscopy, we show that application of acetylcholine (ACh) to the brain surface induces an increase in cerebral blood flow velocity that can be completely blocked by the NO synthase inhibitor NG-nitro-L-arginine. Also sodium nitroprusside, which decomposes to form NO, stimulated cerebral blood flow velocity. The results indicate that NO is a vasodilator in rainbow trout brain, mediating the effect of ACh.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0304-3940
pubmed:author
pubmed:issnType
Print
pubmed:day
15
pubmed:volume
197
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
191-4
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1995
pubmed:articleTitle
Nitric oxide synthase inhibitor blocks acetylcholine induced increase in brain blood flow in rainbow trout.
pubmed:affiliation
Department of Limnology, Uppsala University, Sweden.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't