Linked Life Data

8552289

Source:http://linkedlifedata.com/resource/pubmed/id/8552289

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1996-2-22
pubmed:abstractText
Substituting choline for sodium resulted in an extracellularly recorded transient depolarization and increased efflux of glutamate and adenosine from rat hippocampal slices. The depolarization was blocked by a combination of NMDA and non-NMDA antagonists, MK-801 (10 microM) and 6,7-dinitroquinoxaline-2,3-dione (DNQX, 50 microM). Adenosine release was blocked by MK-801 alone. These data suggest that glutamate released as a result of the sodium removal acts at NMDA and non-NMDA glutamate receptors to trigger the depolarization and acts at NMDA receptors to trigger adenosine release.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0304-3940
pubmed:author
pubmed:issnType
Print
pubmed:day
8
pubmed:volume
197
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
97-100
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1995
pubmed:articleTitle
Choline substitution for sodium triggers glutamate and adenosine release from rat hippocampal slices.
pubmed:affiliation
Department of Physiology, Texas Tech University Health Sciences Center, Lubbock 79430, USA.
pubmed:publicationType
Journal Article, In Vitro, Research Support, U.S. Gov't, P.H.S.