Linked Life Data

8551489

Source:http://linkedlifedata.com/resource/pubmed/id/8551489

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
9
pubmed:dateCreated
1996-2-20
pubmed:abstractText
To examine further the potential role of intracellular cations in hypertension a nested case-control study was carried out in conjunction with a population-based survey. Based on a house-to-house sampling scheme, 43 hypertensive and 56 normotensive black residents of Maywood, IL, were recruited. Free cytosolic calcium (Cai) and intracellular stores of calcium after stimulation with ionomycin were determined in platelets with the fluoroprobe Indo-I; intracellular sodium (Nai) measured at rest and after incubation with ouabain was estimated with SBFI. Cell sodium content was also assayed in erythrocytes. Resting Cai and Nai were not different in hypertensives compared with normotensives, although ionomycin-stimulated levels of Cai were correlated with systolic blood pressure (r = 0.3; P = 0.04). A consistent set of inter-relations among the various cation parameters was observed, lending support to the hypothesis that the cellular metabolism of sodium and calcium may be linked in the pathophysiological pathway to hypertension.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0950-9240
pubmed:author
pubmed:issnType
Print
pubmed:volume
9
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
747-52
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1995
pubmed:articleTitle
Basal and stimulated platelet calcium and sodium in hypertensive versus normotensive black people.
pubmed:affiliation
Department of Preventive Medicine and Epidemiology, Loyola University School of Medicine, Maywood, IL 60153, USA.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.