Linked Life Data

8547458

Source:http://linkedlifedata.com/resource/pubmed/id/8547458

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1996-2-20
pubmed:abstractText
This study aims to investigate whether abnormalities in structural basal ganglia asymmetries in Tourette's syndrome (GTS) have functional significance. Eleven adult GTS patients and 11 normal controls who had participated in the previous MRI study where GTS patients lacked the normal left-greater-than-right (L > R) lenticular asymmetry were re-recruited. They were administered a battery of lateralizing neuropsychological tasks believed to require intact basal ganglia function. GTS subjects lacked normal functional asymmetries on these measures, as predicted. The neuropsychological measures also accounted for a significant portion of the variance in the severity of tic symptoms. These findings suggest that GTS subjects who lack normal basal ganglia structural asymmetries also lack normal functional asymmetries on related neuropsychological measures.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0006-3223
pubmed:author
pubmed:issnType
Print
pubmed:day
15
pubmed:volume
38
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
386-90
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1995
pubmed:articleTitle
Behavioral laterality in individuals with Gilles de la Tourette's syndrome and basal ganglia alterations: a preliminary report.
pubmed:affiliation
Child Study Center, Yale University School of Medicine, New Haven, CT 06520, USA.
pubmed:publicationType
Journal Article, Clinical Trial, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't