| pubmed-article:8546274 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:8546274 | lifeskim:mentions | umls-concept:C0004096 | lld:lifeskim |
| pubmed-article:8546274 | lifeskim:mentions | umls-concept:C0026336 | lld:lifeskim |
| pubmed-article:8546274 | lifeskim:mentions | umls-concept:C0132555 | lld:lifeskim |
| pubmed-article:8546274 | lifeskim:mentions | umls-concept:C0700624 | lld:lifeskim |
| pubmed-article:8546274 | lifeskim:mentions | umls-concept:C0205263 | lld:lifeskim |
| pubmed-article:8546274 | lifeskim:mentions | umls-concept:C0521127 | lld:lifeskim |
| pubmed-article:8546274 | pubmed:issue | 9 | lld:pubmed |
| pubmed-article:8546274 | pubmed:dateCreated | 1996-2-13 | lld:pubmed |
| pubmed-article:8546274 | pubmed:abstractText | We have studied the induction of nitric oxide during late allergic responses, using a guinea pig model of trimellitic anhydride (TMA)-induced airway allergy. TMA is a low molecular weight chemical which can cause occupational asthma. The activity of nitric oxide synthase (NOS) was investigated by the detection of 3H-labeled citrulline formation from 3H-labeled arginine. In sensitized animals, challenge with TMA conjugated to guinea pigs albumin (TMA-GPSA) increased the activity of Ca(2+)-independent NOS (inducible NOS; iNOS) in lung and bronchial tissues at 15-17 h after challenge compared to nonsensitized animals. The induction of iNOS activity was associated with an associated with an increased level of nitrite, an end metabolite of the l-arginine-NO pathway, in bronchoalveolar lavage fluid. In contrast to iNOS, the activity of Ca(2+)-dependent NOS (constitutive NOS; cNOS) was not affected by the allergen challenge. These results demonstrate that iNOS in bronchial tissue is induced late after allergen challenge in sensitized guinea pig. | lld:pubmed |
| pubmed-article:8546274 | pubmed:language | eng | lld:pubmed |
| pubmed-article:8546274 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8546274 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:8546274 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8546274 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8546274 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8546274 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8546274 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:8546274 | pubmed:month | Sep | lld:pubmed |
| pubmed-article:8546274 | pubmed:issn | 0105-4538 | lld:pubmed |
| pubmed-article:8546274 | pubmed:author | pubmed-author:LalM MMM | lld:pubmed |
| pubmed-article:8546274 | pubmed:author | pubmed-author:HanssonG KGK | lld:pubmed |
| pubmed-article:8546274 | pubmed:author | pubmed-author:SkooghB EBE | lld:pubmed |
| pubmed-article:8546274 | pubmed:author | pubmed-author:LötvallJ OJO | lld:pubmed |
| pubmed-article:8546274 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:8546274 | pubmed:volume | 50 | lld:pubmed |
| pubmed-article:8546274 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:8546274 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:8546274 | pubmed:pagination | 760-4 | lld:pubmed |
| pubmed-article:8546274 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:8546274 | pubmed:meshHeading | pubmed-meshheading:8546274-... | lld:pubmed |
| pubmed-article:8546274 | pubmed:meshHeading | pubmed-meshheading:8546274-... | lld:pubmed |
| pubmed-article:8546274 | pubmed:meshHeading | pubmed-meshheading:8546274-... | lld:pubmed |
| pubmed-article:8546274 | pubmed:meshHeading | pubmed-meshheading:8546274-... | lld:pubmed |
| pubmed-article:8546274 | pubmed:meshHeading | pubmed-meshheading:8546274-... | lld:pubmed |
| pubmed-article:8546274 | pubmed:meshHeading | pubmed-meshheading:8546274-... | lld:pubmed |
| pubmed-article:8546274 | pubmed:meshHeading | pubmed-meshheading:8546274-... | lld:pubmed |
| pubmed-article:8546274 | pubmed:meshHeading | pubmed-meshheading:8546274-... | lld:pubmed |
| pubmed-article:8546274 | pubmed:meshHeading | pubmed-meshheading:8546274-... | lld:pubmed |
| pubmed-article:8546274 | pubmed:meshHeading | pubmed-meshheading:8546274-... | lld:pubmed |
| pubmed-article:8546274 | pubmed:meshHeading | pubmed-meshheading:8546274-... | lld:pubmed |
| pubmed-article:8546274 | pubmed:year | 1995 | lld:pubmed |
| pubmed-article:8546274 | pubmed:articleTitle | Induction of nitric oxide synthase in a model of allergic occupational asthma. | lld:pubmed |
| pubmed-article:8546274 | pubmed:affiliation | Department of Clinical Pharmacology, Gothenburg University, Sahlgrens Hospital, Sweden. | lld:pubmed |
| pubmed-article:8546274 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:8546274 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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