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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
9
|
pubmed:dateCreated |
1996-2-7
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pubmed:abstractText |
Two cases of mycosis fungoides (MF) in the tumor stage were treated with intra-lesional interferon-gamma (IFN-gamma) therapy. After systemic chemotherapy, intra-lesional recombinant interferon-gamma was applied to the residual tumors. Intra-lesional IFN-gamma was sufficiently effective in the treatment of MF tumors, especially small-sized ones. Reverse transcriptase polymerase chain reaction (RT-PCR) analysis of messenger RNA expression of cytokines commonly detected interleukin-6 (IL-6) and IFN-gamma in the tumor cells before intra-lesional IFN-gamma. However, in our study, tumor cells in these cases did not exhibit the definitive cytokine patterns of Th1 or Th2.
|
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Sep
|
pubmed:issn |
0385-2407
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
22
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
650-4
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:8537550-Antineoplastic Combined Chemotherapy Protocols,
pubmed-meshheading:8537550-Cytokines,
pubmed-meshheading:8537550-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:8537550-Female,
pubmed-meshheading:8537550-Humans,
pubmed-meshheading:8537550-Injections, Intralesional,
pubmed-meshheading:8537550-Interferon-gamma,
pubmed-meshheading:8537550-Interleukins,
pubmed-meshheading:8537550-Male,
pubmed-meshheading:8537550-Middle Aged,
pubmed-meshheading:8537550-Mycosis Fungoides,
pubmed-meshheading:8537550-Polymerase Chain Reaction,
pubmed-meshheading:8537550-RNA, Messenger,
pubmed-meshheading:8537550-Skin Neoplasms
|
pubmed:year |
1995
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pubmed:articleTitle |
Cytokine profile of tumor cells in mycosis fungoides: successful treatment with intra-lesional interferon-gamma combined with chemotherapy.
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pubmed:affiliation |
Department of Dermatology, Tokyo Medical and Dental University, School of Medicine, Japan.
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pubmed:publicationType |
Journal Article,
Case Reports
|