Linked Life Data

8536109

Source:http://linkedlifedata.com/resource/pubmed/id/8536109

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
9
pubmed:dateCreated
1996-2-7
pubmed:abstractText
We compared the replication of VSV in human umbilical cord vein organ cultures (OC) with that in endothelial cells detached from the vein and infected immediately or infected after 24 h in culture. In four experiments of five, the virus titers obtained in the endothelial cells infected after 24 h in culture were 10-100 times higher than in the OC and 100-1000 times higher than in the freshly detached endothelial cells. To determine whether production of IFN, TNF, and IL-6 in the various cultures correlated with the data for virus yields, we measured the amounts of these cytokines formed. The OC produced considerably larger amounts of all of these. The endothelial cells produced very little IFN and TNF. Overall, there was no clear correlation between virus production and the amounts of these cytokines formed.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
1079-9907
pubmed:author
pubmed:issnType
Print
pubmed:volume
15
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
811-4
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
1995
pubmed:articleTitle
Production of cytokines with antiviral activity by endothelial cells.
pubmed:affiliation
Laboratory of Virology, Polish Academy of Sciences, Wroc?aw, Poland.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't