Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1-2
pubmed:dateCreated
1996-1-31
pubmed:abstractText
This report describes the immunocytochemical detection and distribution of different canine leucocytes antigens (Thy-1, CD5, CD4, CD8, MHC-II and B-cell antigen) by means of monoclonal antibodies (mAbs) in frozen tissue sections of lymphoid organs of the dog. CD5 is expressed exclusively by T lymphocytes. Thy-1 is expressed by T-lymphocytes and in a variety of non-lymphoid tissues. The mAb against canine MHC-II could detect B and T lymphocytes, macrophages, fibroblasts and antigen presenting cells. The CD4 antigen is expressed on many lymphocytes of the T-dependent areas of lymph organs and is also expressed by certain antigen presenting cells. CD8 is expressed in a minor proportion of T cells. The mAb against B cells detected lymphocytes in lymphoid follicles and epithelial cells of the thymic medulla.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0165-2427
pubmed:author
pubmed:issnType
Print
pubmed:volume
47
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
13-23
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1995
pubmed:articleTitle
Immunohistochemical detection of canine leucocyte antigens by specific monoclonal antibodies in canine normal tissues.
pubmed:affiliation
Departament de Patologia i Producció Animals, Facultat de Veterinària, Universitat Autònoma de Barcelona, Bellaterra, Spain.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't