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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5244
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pubmed:dateCreated |
1996-1-30
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pubmed:databankReference |
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pubmed:abstractText |
Reliable germline transformation is required for molecular studies and ultimately for genetic control of economically important insects, such as the Mediterranean fruit fly (medfly) Ceratitis capitata. A prerequisite for the establishment and maintenance of transformant lines is selectable or phenotypically dominant markers. To this end, a complementary DNA clone derived from the medfly white gene was isolated, which showed substantial similarity to white genes in Drosophila melanogaster and other Diptera. It is correlated with a spontaneous mutation causing white eyes in the medfly and can be used to restore partial eye color in transgenic Drosophila carrying a null mutation in the endogenous white gene.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0036-8075
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
22
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pubmed:volume |
270
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2005-8
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pubmed:dateRevised |
2007-3-19
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pubmed:meshHeading |
pubmed-meshheading:8533095-ATP-Binding Cassette Transporters,
pubmed-meshheading:8533095-Amino Acid Sequence,
pubmed-meshheading:8533095-Animals,
pubmed-meshheading:8533095-Animals, Genetically Modified,
pubmed-meshheading:8533095-Base Sequence,
pubmed-meshheading:8533095-Cloning, Molecular,
pubmed-meshheading:8533095-Diptera,
pubmed-meshheading:8533095-Drosophila Proteins,
pubmed-meshheading:8533095-Drosophila melanogaster,
pubmed-meshheading:8533095-Eye Color,
pubmed-meshheading:8533095-Eye Proteins,
pubmed-meshheading:8533095-Genes, Insect,
pubmed-meshheading:8533095-Genetic Markers,
pubmed-meshheading:8533095-Insect Hormones,
pubmed-meshheading:8533095-Molecular Sequence Data,
pubmed-meshheading:8533095-Mutation,
pubmed-meshheading:8533095-Phenotype,
pubmed-meshheading:8533095-Sequence Alignment,
pubmed-meshheading:8533095-Transformation, Genetic
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pubmed:year |
1995
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pubmed:articleTitle |
The white gene of Ceratitis capitata: a phenotypic marker for germline transformation.
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pubmed:affiliation |
European Molecular Biology Laboratory (EMBL), Heidelberg, Germany.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, Non-U.S. Gov't
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