Linked Life Data

8532367

Source:http://linkedlifedata.com/resource/pubmed/id/8532367

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1996-1-26
pubmed:abstractText
In this review we have summarized the main data concerning Leishmania-macrophage interactions, with particular emphasis on receptors involved in adhesion, activating or deactivating cytokines and toxic molecules responsible for parasite killing. At present it is also known that a different T helper (Th)1- or Th2-cell response may be critical for the outcome of Leishmania infection in human and in murine models. Therefore, we have mentioned the recent studies on cytokines, such as IL-2, which are able to cause the switch from a Th2, disease-promoting immune response, to a Th1, protective response. In fact, in the light of these findings, these molecules may be used in the future for immunotherapeutical or immunoprophylactic purposes.
pubmed:language
ita
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0048-2951
pubmed:author
pubmed:issnType
Print
pubmed:volume
37
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
5-15
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
1995
pubmed:articleTitle
[Leishmania-macrophage interactions: role of cytokines and molecules co-involved in killing].
pubmed:affiliation
Istituto di Malattie Infettive e Parassitarie degli Animali, Università di Bari.
pubmed:publicationType
Journal Article, English Abstract, Review, Research Support, Non-U.S. Gov't