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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
1996-2-1
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pubmed:databankReference |
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pubmed:abstractText |
Several overlapping cDNA clones corresponding to the entire coding sequence of the mouse alpha 1(XI) collagen gene (Col11 a1) were isolated. The conceptual amino acid translation indicated a high degree of sequence identity (93%) with the human alpha 1(XI) chain. The cloning experiments also revealed alternative splicing of the sequence coding for 85 residues located within the acidic region of the amino-globular domain of alpha 1(XI). Analysis of RNA samples from different embryonic tissues suggested that alternative splicing might be confined to tissue destined to become bone.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0888-7543
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
20
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pubmed:volume |
28
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
337-40
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:8530046-Amino Acid Sequence,
pubmed-meshheading:8530046-Animals,
pubmed-meshheading:8530046-Cloning, Molecular,
pubmed-meshheading:8530046-Collagen,
pubmed-meshheading:8530046-DNA, Complementary,
pubmed-meshheading:8530046-Female,
pubmed-meshheading:8530046-Genes,
pubmed-meshheading:8530046-Humans,
pubmed-meshheading:8530046-Male,
pubmed-meshheading:8530046-Mice,
pubmed-meshheading:8530046-Molecular Sequence Data,
pubmed-meshheading:8530046-Muridae,
pubmed-meshheading:8530046-RNA Splicing,
pubmed-meshheading:8530046-Sequence Alignment,
pubmed-meshheading:8530046-Sequence Homology, Amino Acid,
pubmed-meshheading:8530046-Species Specificity,
pubmed-meshheading:8530046-Structure-Activity Relationship
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pubmed:year |
1995
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pubmed:articleTitle |
Coding sequence and alternative splicing of the mouse alpha 1(XI) collagen gene (Col11a1).
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pubmed:affiliation |
Department of Molecular Biology and Biochemistry, Okayama University Medical School, Japan.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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