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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
4
|
| pubmed:dateCreated |
1996-1-29
|
| pubmed:abstractText |
Loperamide is an established treatment of acute diarrhoea with only rare adverse reactions. The pro-drug loperamide oxide is converted to loperamide by anaerobic bacteria in the lower alimentary tract. With the use of loperamide oxide, it was expected to obtain similar antidiarrhoeal efficacy as with loperamide, but with a lower dose and a lower plasma concentration. The incidence of adverse reactions might be reduced with the use of loperamide oxide.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Aug
|
| pubmed:issn |
0269-2813
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
9
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
441-6
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:8527621-Adolescent,
pubmed-meshheading:8527621-Adult,
pubmed-meshheading:8527621-Aged,
pubmed-meshheading:8527621-Diarrhea,
pubmed-meshheading:8527621-Double-Blind Method,
pubmed-meshheading:8527621-Female,
pubmed-meshheading:8527621-Follow-Up Studies,
pubmed-meshheading:8527621-Humans,
pubmed-meshheading:8527621-Loperamide,
pubmed-meshheading:8527621-Male,
pubmed-meshheading:8527621-Middle Aged,
pubmed-meshheading:8527621-Time Factors,
pubmed-meshheading:8527621-Treatment Outcome
|
| pubmed:year |
1995
|
| pubmed:articleTitle |
Loperamide oxide in acute diarrhoea: a double-blind, placebo-controlled trial. The Dutch Diarrhoea Trialists Group.
|
| pubmed:publicationType |
Journal Article,
Clinical Trial,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't
|