Linked Life Data

8527553

Source:http://linkedlifedata.com/resource/pubmed/id/8527553

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1996-2-1
pubmed:abstractText
It is not known how long vaccine-induced type-specific pneumococcal antibodies persist or whether age-related changes in their avidity occur; we therefore administered pneumococcal vaccine to 15 elderly persons aged 60-67 years to determine the level and avidity of the pneumococcal antibodies before vaccination and again 4 weeks and 5 years later. Antibody levels were significantly higher after vaccination than before vaccination in 67% of these subjects (P < .01). On the basis of guidelines established for revaccination, we found that 60% of these elderly persons required revaccination 5 years after primary immunization and that the antibody status of the remaining 40% would need to be determined some years later. No significant differences in IgG antibody avidity were detected in connection with the type of pneumococcus, the vaccination status of the vaccinee (i.e., whether sera were assayed before vaccination or 4 weeks or 5 years later), or the age of the vaccinee.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
1058-4838
pubmed:author
pubmed:issnType
Print
pubmed:volume
21
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
616-20
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1995
pubmed:articleTitle
Quantity and avidity of pneumococcal antibodies before and up to five years after pneumococcal vaccination of elderly persons.
pubmed:affiliation
Streptococcus Department, Statens Seruminstitut, Copenhagen, Denmark.
pubmed:publicationType
Journal Article