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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
12
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pubmed:dateCreated |
1996-1-19
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pubmed:abstractText |
Most pediatric treatment protocols specify dose calculations for cytostatic drugs based on body-surface area (BSA). However, for children less than 1 year of age, calculation guidelines vary. Normally, reduced dosages are recommended with calculations based on body weight (BW). However, the optimal dose for infants should take age-dependent and drug-specific pharmacokinetic parameters into account.
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pubmed:language |
eng
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pubmed:journal |
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|
pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0732-183X
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:volume |
13
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2954-60
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:8523060-Adolescent,
pubmed-meshheading:8523060-Aging,
pubmed-meshheading:8523060-Body Surface Area,
pubmed-meshheading:8523060-Body Weight,
pubmed-meshheading:8523060-Bone Marrow Diseases,
pubmed-meshheading:8523060-Child,
pubmed-meshheading:8523060-Child, Preschool,
pubmed-meshheading:8523060-Dose-Response Relationship, Drug,
pubmed-meshheading:8523060-Etoposide,
pubmed-meshheading:8523060-Humans,
pubmed-meshheading:8523060-Individuality,
pubmed-meshheading:8523060-Infant,
pubmed-meshheading:8523060-Infusions, Intravenous,
pubmed-meshheading:8523060-Neuroblastoma
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pubmed:year |
1995
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pubmed:articleTitle |
Steady-state levels and bone marrow toxicity of etoposide in children and infants: does etoposide require age-dependent dose calculation?
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pubmed:affiliation |
Department of Pediatric Hematology and Onkology, University of Münster, Germany.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
Research Support, Non-U.S. Gov't,
Multicenter Study
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