Linked Life Data

8518941

Source:http://linkedlifedata.com/resource/pubmed/id/8518941

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1993-7-29
pubmed:abstractText
The distribution of calcitonin gene-related peptide (CGRP)-immunoreactive neurones was examined in the hypothalamus and pituitary gland of the short-term ovariectomised ewe. A large number of magnocellular CGRP-immunoreactive neurones were identified in the ventral paraventricular nuclei (PVN); few were found in the dorsal PVN and supraoptic nuclei. Parvicellular CGRP-immunoreactive neurones were identified in low density scattered throughout the preoptic region, anterior and basal hypothalamus and region of the stria terminalis. A dense CGRP innervation of the median eminence and neural lobe of the pituitary was observed. These observations reveal substantial species differences in CGRP immunoreactivity compared with the rat and show that magnocellular CGRP-synthesising neurones in the sheep are essentially restricted to, and define, the ventral PVN. This suggests a functionally distinct role for this previously neglected division of the PVN within the ovine hypothalamo-neurohypophyseal system.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0006-8993
pubmed:author
pubmed:issnType
Print
pubmed:day
14
pubmed:volume
611
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
147-51
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1993
pubmed:articleTitle
Calcitonin gene-related peptide (CGRP): immunocytochemical identification of a neuropeptide synthesised by ventral paraventricular magnocellular neurones in the sheep.
pubmed:affiliation
Department of Neurobiology, AFRC Institute of Animal Physiology, Babraham, Cambridge UK.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't