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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
|
pubmed:dateCreated |
1993-7-21
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pubmed:abstractText |
The penetration of oral 1000 mg/day ciprofloxacin into pleural fluid is investigated in 15 patients with exudative pleural effusion. After 4 days of ciprofloxacin therapy ciprofloxacin concentrations were measured in plasma and pleural exudate simultaneously by high-performance liquid chromatography (HPLC). Mean serum ciprofloxacin level was 1.58 +/- 0.91 mg/L and mean pleural exudate concentration was 1.00 +/- 0.59 mg/L. The concentrations achieved were all above the MIC90 of the majority of Gram-positive and Gram-negative pathogens. It is concluded that ciprofloxacin penetrates well into the pleural fluid.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
1120-009X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
5
|
pubmed:owner |
NLM
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pubmed:authorsComplete |
N
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pubmed:pagination |
110-2
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pubmed:dateRevised |
2009-8-4
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pubmed:meshHeading |
pubmed-meshheading:8515292-Adolescent,
pubmed-meshheading:8515292-Adult,
pubmed-meshheading:8515292-Aged,
pubmed-meshheading:8515292-Aged, 80 and over,
pubmed-meshheading:8515292-Ciprofloxacin,
pubmed-meshheading:8515292-Female,
pubmed-meshheading:8515292-Humans,
pubmed-meshheading:8515292-Male,
pubmed-meshheading:8515292-Middle Aged,
pubmed-meshheading:8515292-Pleural Effusion
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pubmed:year |
1993
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pubmed:articleTitle |
Penetration of ciprofloxacin into pleural fluid.
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pubmed:affiliation |
Department of Pulmonary Disease, Cerrahpasa Medical Faculty, Istanbul University, Turkey.
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pubmed:publicationType |
Journal Article
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