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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
1993-7-22
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pubmed:abstractText |
An O-acetylated ganglioside that generated a trisialyllactosylceramide or GT3 by base treatment was found for the first time in cod fish brain. This ganglioside was isolated by high-performance liquid chromatography, and characterized by fast atom bombardment mass spectrometry, and proton nuclear magnetic resonance spectroscopy in addition to chemical analysis. The structure was identified as a modified GT3 in which the external sialic acid is O-acetylated at the C-9 position. The chemical structure is as follows: II3(9-O-Ac-NeuAc2-8NeuAc2-8NeuAc2-3)Lac Cer.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0021-924X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
113
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
502-7
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pubmed:dateRevised |
2007-12-19
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pubmed:meshHeading |
pubmed-meshheading:8514740-Acetylation,
pubmed-meshheading:8514740-Animals,
pubmed-meshheading:8514740-Brain Chemistry,
pubmed-meshheading:8514740-Chromatography, High Pressure Liquid,
pubmed-meshheading:8514740-Chromatography, Thin Layer,
pubmed-meshheading:8514740-Fishes,
pubmed-meshheading:8514740-Gangliosides,
pubmed-meshheading:8514740-Lactosylceramides,
pubmed-meshheading:8514740-Magnetic Resonance Spectroscopy,
pubmed-meshheading:8514740-Mass Spectrometry,
pubmed-meshheading:8514740-Molecular Structure,
pubmed-meshheading:8514740-N-Acetylneuraminic Acid,
pubmed-meshheading:8514740-Sialic Acids
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pubmed:year |
1993
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pubmed:articleTitle |
Isolation and characterization of a trisialyllactosylceramide, GT3, containing an O-acetylated sialic acid in cod fish brain.
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pubmed:affiliation |
Department of Membrane Biochemistry, Tokyo Metropolitan Institute of Gerontology.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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