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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
1993-7-22
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pubmed:abstractText |
Calbindin-D28k, a calcium-binding protein, has been identified within a subpopulation of midbrain dopaminergic (DA) neurons in rats, monkeys and humans. The neuroactive peptides CCK and neurotensin also have been found in a subpopulation of midbrain DA neurons. Using double- and triple-labeling immunocytochemical staining procedures in the rat, we now report that the midbrain DA neurons that contain the peptides also contain calbindin-D28k. Calbindin-D28k may play a role in the co-release of neuroactive peptides with dopamine from the midbrain DA neurons.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0959-4965
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
4
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
491-4
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:8513124-Animals,
pubmed-meshheading:8513124-Calcium-Binding Protein, Vitamin D-Dependent,
pubmed-meshheading:8513124-Cholecystokinin,
pubmed-meshheading:8513124-Dopamine,
pubmed-meshheading:8513124-Immunohistochemistry,
pubmed-meshheading:8513124-Male,
pubmed-meshheading:8513124-Mesencephalon,
pubmed-meshheading:8513124-Neurons,
pubmed-meshheading:8513124-Neuropeptides,
pubmed-meshheading:8513124-Neurotensin,
pubmed-meshheading:8513124-Rats
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pubmed:year |
1993
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pubmed:articleTitle |
Neuroactive peptides exist in the midbrain dopaminergic neurons that contain calbindin-D28k.
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pubmed:affiliation |
Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas 75235-9070.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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