Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1993-7-12
pubmed:abstractText
The aim of this investigation was to determine whether nicotine exposure (1 mg/kg body mass/d) during pregnancy and lactation contributes to the rupturing of alveolar septa in the lungs of neonatal rats. These rats received nicotine only via the placenta and mother's milk. The results show that maternal nicotine exposure interferes with elastic tissue formation. It also interferes with alveoli formation and causes the development of emphysema-like lesions. It is therefore suggested that maternal nicotine intake from smoking during pregnancy and lactation may interfere with lung development and maturation to an extent that increases susceptibility to emphysema.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0256-9574
pubmed:author
pubmed:issnType
Print
pubmed:volume
83
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
195-8
pubmed:dateRevised
2004-9-28
pubmed:meshHeading
pubmed:year
1993
pubmed:articleTitle
Maternal nicotine exposure during pregnancy and development of emphysema-like damage in the offspring.
pubmed:affiliation
Department of Physiological Sciences, University of the Western Cape, Bellville, CP.
pubmed:publicationType
Journal Article