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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
7
|
| pubmed:dateCreated |
1993-7-13
|
| pubmed:abstractText |
Following the finding in 1990 of six HTLV-I-positive cases of tropical spastic paraparesis (TSP/HAM) is a field survey carried out in the city of Inongo (Bandundu, Zaire), the prevalence of HTLV-I infection has been studied by detection of specific antibodies on a randomized sample of the general population. Among the 1,162 subjects surveyed, 36 (3.1%) were found to be HTLV-I seropositive, giving a seroprevalence of 3.2% (CI: 2.1, 4.3) estimated by direct standardization on age and sex distribution given by the census in the city. Among the five major ethnic groups, the Bolia showed the highest prevalence rate (6.5%) but with no detected TSP/HAM cases, while all six TSP/HAM cases were found among the Ntomba, who showed a prevalence rate of only 2.2%. This finding suggests that besides HTLV-I infection, critical environmental and/or genetic cofactors play a part in the development of TSP/HAM.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jul
|
| pubmed:issn |
0894-9255
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
6
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
840-4
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:8509984-Adolescent,
pubmed-meshheading:8509984-Adult,
pubmed-meshheading:8509984-Age Factors,
pubmed-meshheading:8509984-Aged,
pubmed-meshheading:8509984-Carrier State,
pubmed-meshheading:8509984-Child,
pubmed-meshheading:8509984-Child, Preschool,
pubmed-meshheading:8509984-Cluster Analysis,
pubmed-meshheading:8509984-Democratic Republic of the Congo,
pubmed-meshheading:8509984-Ethnic Groups,
pubmed-meshheading:8509984-Female,
pubmed-meshheading:8509984-HTLV-I Antibodies,
pubmed-meshheading:8509984-HTLV-I Infections,
pubmed-meshheading:8509984-Humans,
pubmed-meshheading:8509984-Infant,
pubmed-meshheading:8509984-Male,
pubmed-meshheading:8509984-Middle Aged,
pubmed-meshheading:8509984-Multivariate Analysis,
pubmed-meshheading:8509984-Paraparesis, Tropical Spastic,
pubmed-meshheading:8509984-Prevalence,
pubmed-meshheading:8509984-Risk Factors,
pubmed-meshheading:8509984-Sex Factors
|
| pubmed:year |
1993
|
| pubmed:articleTitle |
The risk of tropical spastic paraparesis differs according to ethnic group among HTLV-I carriers in Inongo, Zaire.
|
| pubmed:affiliation |
Unité d'Epidémologie des Virus Oncogénes and URA 1157 CNRS, Institut Pasteur, Paris, France.
|
| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|