Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1993-7-2
pubmed:abstractText
This study represents the first report indicating that rat heart microsomes contain a measurable delta-6-desaturase activity. The aging process affects delta-6-desaturase activity in the heart to a lesser extent than in the liver, supporting the hypothesis that the regulation of the individual desaturase enzymes may differ in these two tissues. Although decreased desaturase activity, considered alone, may be expected to lower polyunsaturated fatty acid levels, in old animals no modifications in heart microsome fatty acid composition were observed. Probably other metabolic changes may offset this effect, leading to the maintenance of arachidonic acid level in the heart.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0006-291X
pubmed:author
pubmed:issnType
Print
pubmed:day
14
pubmed:volume
192
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1037-41
pubmed:dateRevised
2009-11-19
pubmed:meshHeading
pubmed:year
1993
pubmed:articleTitle
Evidence for a detectable delta-6-desaturase activity in rat heart microsomes: aging influence on enzyme activity.
pubmed:affiliation
Departamento de Fisiologia y Farmacologia (Facultad de Biologia), University of Murcia, Spain.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't