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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
1993-7-8
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pubmed:abstractText |
An iminium salt of octaethylbenzochlorin with copper in the aromatic ring, CDS1, was tested for its tumoricidal effects on the AY-27 N-[4-(5-nitro-2-furyl)-2-thiazolyl] formamide tumor line. CDS1 was found to be an effective photosensitizer in vivo when used in combination with either a xenon arc lamp or a pulsed alexandrite laser. Hemodynamically, CDS1 and light caused a rapid decrease in tumor blood flow. Skin photosensitization was found to be minimal when drug-injected mice were illuminated in a solar simulator.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Apr
|
pubmed:issn |
0031-8655
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
57
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
681-5
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:8506398-Animals,
pubmed-meshheading:8506398-Deuteroporphyrins,
pubmed-meshheading:8506398-Imines,
pubmed-meshheading:8506398-Light,
pubmed-meshheading:8506398-Male,
pubmed-meshheading:8506398-Mice,
pubmed-meshheading:8506398-Mice, Hairless,
pubmed-meshheading:8506398-Molecular Structure,
pubmed-meshheading:8506398-Photochemotherapy,
pubmed-meshheading:8506398-Photosensitizing Agents,
pubmed-meshheading:8506398-Rats,
pubmed-meshheading:8506398-Rats, Inbred F344,
pubmed-meshheading:8506398-Skin,
pubmed-meshheading:8506398-Urinary Bladder Neoplasms
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pubmed:year |
1993
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pubmed:articleTitle |
Copper benzochlorin, a novel photosensitizer for photodynamic therapy: effects on a transplantable urothelial tumor.
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pubmed:affiliation |
Department of Urology, Medical College of Ohio.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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